Vaccine Autism Shocker: Study Reports Strong Evidence of Autism Connection to Aluminum and Acetaminophen Exposure

It is quite possible that a paper claiming that empirical data confirm autism symptoms are related to Aluminum and Acetaminophen exposure, and possibly to the MMR vaccine,  could put the research standing and careers of the authors in jeopardy.  The paper in the journal Entropy is tantamount to treason in some health circles and could invite serious retribution from those who have elevated vaccines to a level beyond criticism.  

The researchers, to my great surprise, did not try to sugar coat their findings in  Empirical Data Confirm Autism Symptoms Related toAluminum and Acetaminophen Exposure, published in Entropy, November 7, 2012: 

Abstract: Autism is a condition characterized by impaired cognitive and social skills, associated with compromised immune function. The incidence is alarmingly on the rise, and environmental factors are increasingly suspected to play a role. This paper investigates word frequency patterns in the U.S. CDC Vaccine Adverse Events Reporting System (VAERS) database. Our results provide strong evidence supporting a link between autism and the aluminum in vaccines. A literature review showing toxicity of aluminum in human physiology offers further support. Mentions of autism in VAERS increased steadily at the end of the last century, during a period when mercury was being phased out, while aluminum adjuvant burden was being increased. Using standard log-likelihood ratio techniques, we identify several signs and symptoms that are significantly more prevalent in vaccine reports after 2000, including cellulitis, seizure, depression, fatigue, pain and death, which are also significantly associated with aluminum-containing vaccines. We propose that children with the autism diagnosis are especially vulnerable to toxic metals such as aluminum and mercury due to insufficient serum sulfate and glutathione. A strong correlation between autism and the MMR (Measles, Mumps, Rubella) vaccine is also observed, which may be partially explained via an increased sensitivity to acetaminophen administered to control fever.

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6. Conclusion 

In this paper, we have presented some analyses of the VAERS database which strongly suggest that the aluminum in vaccines is toxic to vulnerable children. While we have not shown that aluminum is directly causative in autism, the compelling evidence available from the literature on the toxicity of aluminum, combined with the evidence we present for severe adverse reactions occurring much more frequently following administration of aluminum-containing vaccines as compared to non-aluminumcontaining vaccines, suggests that neuronal damage due to aluminum penetration into the nervous system may be a significant factor in autism. The fact that mentions of autism rose steadily concomitant with significant increases in the aluminum burden in vaccines, is highly suggestive. However, it is possible that other factors, such as more aggressive reporting or simultaneous increases in other environmental toxins, e.g., herbicides or pesticides, or aluminum in other products such as antiperspirants and antacids, may have contributed to these observed increases. We also observed a strong correlation between the MMR vaccine and autism, which we suggest could be explained by the effects of acetaminophen. 

We have proposed elsewhere that an impairment in cholesterol sulfate synthesis in the skin and in the vasculature may be causative in autism, and we argue here that vaccines can act synergistically with this impairment in the vulnerable child. We propose that simple corrective measures such as increased sunlight exposure and decreased use of sunscreen may help protect a child from a severe reaction to aluminum-containing vaccines, but we also feel that the vaccine industry should find a way to reduce or even eliminate the aluminum content in vaccines. 

As might be expected Dr. David H. Gorski, writing under the handle Orac has already spewed some venom on  one of the authors of the study in his blog commentary of November 20, 2012, Stephanie Seneff: Following the Geiers dumpster-diving in the VAERS database.  I am not sure why Gorski engages in the childish, self inflating style that he does. There is no question he has a loyal following but I doubt very much that he is persuading parents or others with vaccine concerns to abandon those concerns and vaccinate themselves and their children.   I suspect his venomous hostility is actually counter productive.

I have received the usual recommended vaccines and so have both of my sons. I have never suspected vaccines as contributing factors to my younger son's severe autistic disorder and profound developmental delays although I have not closed my mind on the possibility either should further research demonstrate such a connection.  I believe that more research is needed to persuade those with concerns and, if connections are shown, to recommend study and changes to eliminate those possible connections.

What I don't recommend is the strategy of attacking vaccine safety skeptics and expecting the attacks to change their minds.  That approach simply has not worked. A much better scientist than David Gorski, a gentleman named Albert Einstein, characterized "doing the same thing over and over again and expecting different results" as a form of insanity.   I don't expect Orac to change his approach. Nor do I expect the results of his attacks to yield different results.  What would be helpful is to have the Seneff study findings properly rebutted or, if confirmed, the problems they point to addressed.

Autism and the MMR Vaccine:Was Wakefield Confirmed by Wake Forest University School of Medicine Study?

UPDATE: The question in my comment title was answered, to some extent, by information passed to me that this study was reported in 2007. I have no idea why it shows up on the Daily Mail online with today's date at the top of the page and with no internal story dates to indicate it is not current. It also shows up in Google News.  


I did a web search by the author's name and found the same article published in different places on the web on different dates. What I haven't found is what happened to the Wake Forest study?  If anyone knows feel free to offer your information. HLD


According to a report in the UK Daily Mail, Scientists fear MMR link to autism,  a study led by Dr. Stephen Walker of  the Wake Forest University School of Medicine in North Carolina appears to confirm findings in the much maligned 1998 study by Dr. Andrew Wakefield. The research team are examining 275 children with regressive autism and bowel disease and,  of 82 tested so far,  70 prove positive for the vaccine strain, not the wild strain, of the measles virus. The report also indicates that the this is the second study including the O'Leary 2001 study to confirm the Wakefield findings:

"Last night the team's leader, Dr Stephen Walker, said: 'Of the handful of results we have in so far, all are vaccine strain and none are wild measles.

'This research proves that in the gastrointestinal tract of a number of children who have been diagnosed with regressive autism, there is evidence of measles virus.

'What it means is that the study done earlier by Dr Wakefield and published in 1998 is correct. That study didn’t draw any conclusions about specifically what it means to find measles virus in the gut, but the implication is it may be coming from the MMR vaccine. If that’s the case, and this live virus is residing in the gastrointestinal tract of some children, and then they have GI inflammation and other problems, it may be related to the MMR.'

The 1998 study by Dr Wakefield, then a reader in gastroenterology at the Royal Free Hospital in North London, and 12 other doctors claimed to have found a new bowel disease, autism enterocolitis.

At the time, Dr Wakefield said that although they had not proved a link between MMR (measles, mumps, rubella) and autism, there was cause for concern and the Government should offer the option single vaccines - instead of only MMRs - until more research had been done.

The paper - and the confused interpretation of its findings - caused uproar and led to many parents withdrawing their co-operation for the triple jab. Ten of the paper's authors also signed retractions on the interpretation but stood by the science.

This is the second independent study to back up Dr Wakefield. In 2001 John O'Leary, Professor of Pathology at St James's Hospital and Trinity College, Dublin, replicated his findings.

Last night Dr Wakefield said: 'This new study confirms what we found in British children and again with Professor O'Leary. The only exposure these children have had to measles is through the MMR vaccine.

'They were developing normally until they regressed. They now suffer autism and bowel disease."'The Department of Health and some of the media wanted to dismiss our research as insignificant. The excuse was that no one else had the same findings as us. What they didn't say is that no one else had looked."

This study will be subjected to very close scrutiny.  Not just because it might implicate vaccines in some instances of autism, and should be examined closely as part of the scientific method,  but also because a war has been waged on Dr. Andrew Wakefield.  Those who have waged that war have much to lose if the information reported by the Daily Mail is confirmed.  Their own reputations are now on the line. They  can not,  and will not,  accept any study or information which calls into question their efforts to discredit Wakefield and his study. 

So Much For Due Process: TimesOnline Convicts Wakefield Of Fixing Autism Data

In England, the land where the common law was born that ultimately provided the foundation for legal systems around the world, including the United States, Canada and Australia, due process is apparently viewed by the media as a quaint historical relic. At least one could reasonably reach that conclusion after reading MMR doctor Andrew Wakefield fixed data on autism published February 8 2009 on TIMESONLINE. Dr. Wakefield, with two professors, John Walker-Smith and Simon Murch, is currently facing charges of serious professional misconduct brought by the General Medical Council (GMC).

Wakefield and the two professors deny the allegations but the TIMESONLINE, in an article by Brian Deer, has apparently decided to dispense with old fashioned notions of due process and is informing the world of its verdict:

"Andrew Wakefield manipulated patients’ data, which triggered fears that the MMR triple vaccine to protect against measles, mumps and rubella was linked to the condition.

...

The research was published in February 1998 in an article in The Lancet medical journal. It claimed that the families of eight out of 12 children attending a routine clinic at the hospital had blamed MMR for their autism, and said that problems came on within days of the jab. The team also claimed to have discovered a new inflammatory bowel disease underlying the children’s conditions.

However, our investigation, confirmed by evidence presented to the General Medical Council (GMC), reveals that: In most of the 12 cases, the children’s ailments as described in The Lancet were different from their hospital and GP records. Although the research paper claimed that problems came on within days of the jab, in only one case did medical records suggest this was true, and in many of the cases medical concerns had been raised before the children were vaccinated. Hospital pathologists, looking for inflammatory bowel disease, reported in the majority of cases that the gut was normal. This was then reviewed and the Lancet paper showed them as abnormal."

These are obviously very serious allegations. Perhaps I am biased, being a humble, small town lawyer in New Brunswick, Canada but I prefer to await the decision of the tribunal before reporting the verdict.

autism

In Praise of Jenny McCarthy

I do not share Jenny McCarthy's views on the MMR vaccine and autism.

Nor do I believe that she any better able to assess the evidence or the scientific literature on the subject than any other parent of an autistic child. But she does have the gift of celebrity status, the power to command media attention and disseminate her views. And it is harder to get better media attention than to appear on Oprah Winfrey's show. Much more effectively than this humble small town blogger can do. Although I disagree with her views though, I admire her willingness to fight for her child. Ms McCarthy has not embraced the culture of defeat, the attraction of the sweet surrender, of giving in and convincing yourself that there is joy in autism, a profoundly disabling neurological disorder. For that refusal to imbibe the kool aid of the cult of defeat Ms McCarthy deserves credit.

In speaking out and expressing her views on MMR vaccines and autism Ms McCarthy surely knew that she would be the object of ridicule. Some of the commentary is snide, some of it is out and out mean spirited and belittles only those who offer it. A cheap shot artist is a cheap shot artist, whether they sport a Ph. D. or not. Ms McCarthy spoke out to express her beliefs in support of helping her child. A noble cause. And she, and Ms Winfrey who hosted her on her show, are nobler for fighting for that cause. As for Ms McCarthy's friend Jim Carrey I know what it means to be an autism dad by fate. Mr Carrey has freely chosen to take on that role and also earned my admiration.

I don't agree with Ms McCarthy's MMR autism views, although future evidence could still prove her right and me wrong. But I admire her fight for her child, and Ms Winfrey for helping and Mr Carrey for caring and taking on the challenge.

Well done; all three of you.

Autism Surge & Vaccines - It Ain't Over Til It's Over

"It ain't over til it's over"" - Yogi Berra

Even as the mercury autism proceedings unfold in the US and long after I had thought the issue of vaccines and autism was no longer a serious issue comes word of another big surge in autism cases and more expressions of belief by health care professionals that the surge is linked to vaccines. The UK autism figures are surprising. The 1 in 150 figure from the CDC in the US has given way in the UK to 1 in 100, with some sources reporting 1 in 86, and now one report indicating 1 in 58. Why is the UK rate so much different from that reported by the CDC? IF there is a real difference between the American and UK figures, and not just differences in reporting or diagnosis, what could explain the differences other than environmental factors? Some medical professionals in the UK are again pointing to vaccines. The scientific and professional debate might be refueled by this news but will pale in comparison to the inter-net wars between the mercury causes autism believers and the Neurodiversity camp. Fasten your seat belts folks we will soon be experiencing more autism turbulence.

Whatever the explanation for the UK surge in autism figures it is clear that the world still has much to learn about autism, rates of autism and the big question what causes, or what group of factors, cause autism? As the great sage Yogi Berra said "it ain't over til its over".


New health fears over big surge in autism

· Experts 'concerned' by dramatic rise
· Questions over triple jab for children

Denis Campbell, health correspondent
Sunday July 8, 2007
The Observer

The number of children in Britain with autism is far higher than previously thought, according to dramatic new evidence by the country's leading experts in the field.

A study, as yet unpublished, shows that as many as one in 58 children may have some form of the condition, a lifelong disability that leads to many sufferers becoming isolated because they have trouble making friends and often display obsessional behaviour.

Seven academics at Cambridge University, six of them from its renowned Autism Research Centre, undertook the research by studying children at local primary schools. Two of the academics, leaders in their field, privately believe that the surprisingly high figure may be linked to the use of the controversial MMR vaccine. That view is rejected by the rest of the team, including its leader, the renowned autism expert, Professor Simon Baron-Cohen.

The team found that one in 58 children has either autism or a related autistic spectrum disorder. Nationwide, that could be as many as 210,000 children under 16. The research is significant because that figure is well above the existing estimate of one in 100, which specialist bodies such as the National Autistic Society have until now accepted as correct. It is also significantly more than the previous highest estimate of one in 86, which was reported in research published last year in the Lancet.

Some experts who previously explained the rise in autism as the result of better diagnosis and a broader definition of the condition now believe the upward trend revealed by studies such as this indicates that there has been a real rise in the numbers of children who are affected by it. Although the new research is purely statistical and does not examine possible explanations for the rise, two of the authors believe that the MMR jab, which babies receive at 12 to 15 months, might be partly to blame. Dr Fiona Scott and Dr Carol Stott both say it could be a factor in small numbers of children.

Professor Baron-Cohen, director of the centre and the country's foremost authority on the condition, said he did not believe there was any link between the three-in-one vaccination and autism. Genetics, better recognition of the condition, environmental factors such as chemicals and children's exposure to hormones in the womb, especially testosterone, were more likely to be the cause, he commented. 'As for MMR, at this point one can conclude that evidence does not support the idea that the MMR causes autism.'

Baron-Cohen and his team studied the incidence of autism and autistic spectrum disorders among some 12,000 children at primary school in Cambridgeshire between 2001 and 2004. He was so concerned by the one in 58 figure that last year he proposed informing public health officials in the county.

Controversy over the MMR jab erupted in 1998 after Dr Andrew Wakefield, a gastroenterologist at the Royal Free Hospital in north London, said he no longer believed it was safe and might cause autism and inflammatory bowel disease in children. Many parents panicked and MMR take-up fell dramatically. More families opted to have their child immunised privately through three separate injections to avoid the possibility of their immune system being overloaded by the MMR jab, thus leaving them at greater risk of infections.

The medical and scientific establishment denied Wakefield's claim, described research he had co-authored as 'bad science', and sought to reassure the public, with limited success. Wakefield and two former Royal Free colleagues are due to appear before the General Medical Council next week to answer charges relating to the 1998 research. The trio could be struck off.

The doctors' disciplinary body claims that Wakefield acted 'dishonestly and 'irresponsibly' in dealings with the Lancet, was 'misleading' in the way he sought research funding from the Legal Aid Board, and 'acted unethically and abused his position of trust as a medical practitioner' by taking blood from children after offering them money.

A book to be published this month by Dr Richard Halvorsen, a London GP who provides single vaccines privately to babies of parents concerned about MMR, will fuel the controversy. It will present new evidence of children allegedly being damaged by vaccinations and linking increased autism to MMR.

But Dr David Salisbury, national director for vaccines and immunisation at the Department of Health, said last night: 'The evidence is absolutely clear. No published study has ever shown a link between autism and the MMR vaccine. It is absolute nonsense to suggest otherwise.

Autism, Vaccines & the Spread of Mumps - Eastern Canada

The belief that some vaccines, or mercury based vaccine preservatives, cause or contribute to today's increasing autism rates, now estimated at 1 in 150, persists despite an almost total lack of support in the scientific community for any causal connection. The fear generated by that belief is itself believed to have contributed to higher rates of vaccine refusals with resulting increases in diseases such as measles and mumps. In Atlantic Canada we are currently suffering an outbreak of mumps, with the particular strain of mumps having orginated in the UK where immunization rates dropped from fear that the measles-mumps-rubella vaccine caused autism.

Health: ALERT: INFECTIONS

Mumps outbreak spreads

CAROLINE ALPHONSO

May 11, 2007

Nova Scotia's mumps outbreak has spread to Ontario, infecting five people so far and putting public-health officials in the province on alert for even more cases in the weeks to come.

The latest outbreak indicates that many who were vaccinated years ago are now susceptible to catching the disease. Public-health officials are now debating whether they need to administer a booster shot.

Ontario's Ministry of Health and Long-Term Care confirmed yesterday that the cases, two of which are in Toronto, are linked to the outbreak in Nova Scotia, where more than 200 people have been infected by the disease. The outbreak, which began in late February, has also infected 34 people in New Brunswick and one in Prince Edward Island.

...

Neil Rau, an infectious disease specialist at Halton Healthcare Services in Ontario, said the current strain of mumps originated in Britain, where there was a large outbreak in 2004. Immunization rates had drop significantly in Britain because many people believed the measles-mumps-rubella vaccine caused autism. The vaccine-autism link has since been disproved, he noted.

The disease reached Iowa last year, and Dr. Rau said it has now found its way into Canada.

"It's global travel compounded with vaccine refusal," he said.

http://tinyurl.com/3b49fz

Evidence of Harm - The Sequel

In recent years theories that autism increases have been caused by either the MMR vaccine itself or thimerosal, the mercury based vaccine preservative, once more widely used, has dominated much public discussion of autism - despite an almost total lack of support for the vaccine causes autism theories amongst the world scientific community. But the controversy generated by the Wakefield study and the David Kirby/Robert Kennedy Jr anti-mercury campaigns has had an impact - on famlies already stressed by the realities of their children's autism and on a decline, at least temporarily, in the numbers of persons getting their children vaccinated against serious, dangerous diseases. Evidence of harm? You bet. Not the kind Kirby and Company rant about on the Huffington post though.

http://www.news-medical.net/?id=22732


Study reveals impact of the MMR controversy on parents of children with autism
Medical Studies/Trials

Published: Thursday, 29-Mar-2007

Researchers have found that the MMR controversy caused parents of children with autism feelings of stress, guilt and frustration. Their study is published in Archives of Disease Childhood.

In the course of 10 focus group discussions across the UK between 2003 and 2005 involving 38 parents of children with autism, scientists from the Medical Research Council (MRC) discovered the effects of the uncertainty caused by the MMR controversy on these parents. Their aim was to assess how the parents had been affected and identify their specific needs to inform how these might be met in future debates around immunisation.

In 1998, Andrew Wakefield and his colleagues published an article in which they claimed to have found a link between the MMR vaccine and the onset of autistic spectrum disorder, although most of his co-authors subsequently disassociated themselves from the suggestion that there was a link between the vaccine and autism.

The controversy that followed affected parents' decision-making with regards to MMR vaccination. The Health Protection Agency's figures show immunisation rates across the UK population fell from 92% before the controversy, to 80% by 2003/04 (http://www.hpa.org.uk/infections/topics_az/vaccination/cover.htm). Vaccination rates have since started to increase again as parental confidence in the vaccine has begun to recover. However, until now no research had looked at the impact of the MMR controversy on the parents of children with autism.

Dr Shona Hilton and her colleagues at the MRC Social and Public Health Sciences Unit in Glasgow found that many parents of children with autism have come under great stress and pressure as a result of the scare.

Dr Hilton found that some have experienced agonising uncertainty as to whether the MMR vaccine may have provoked their child's or children's autism. Many have wondered whether they are to blame for their child's condition or felt they had "let their children down" by deciding to vaccinate. Even those who felt that their child's autism was not linked to the MMR vaccine, either because of family history or because they had avoided vaccination, had suffered as a result of the ambiguous advice they felt that they had received.

The discussions also showed that most parents found it extremely difficult to make subsequent decisions about further vaccination for their children with autism and later children. Many parents felt let down by health professionals and health visitors as well as GPs. This appeared to be a result of the lack of clarity and consistency in what they were told. It may also have been a result of the perceived lack of empathy with and understanding of the realities of caring for a child with autism.

Dr. Hilton said: "It is clear from a review of the literature that there has been a lack of follow-up of the impact of this health scare on those likely to be most directly affected - those living day in and day out with children with autism. These parents in particular have been under a huge amount of stress about the possible impact of their decision to vaccinate or not. Often, those they turned to for guidance and advice, their health visitors and GPs, were not able to provide them with the support they needed.

Dr Hilton added "we are planning to conduct further research into whether health professionals feel that they are well-enough equipped to deal with parents during such health controversies, and how they can be better-supported. We hope to be able to develop new information materials and to identify other support that health professionals need in the difficult task they face of communicating with parents at the height of any future health controversies."

http://www.mrc.ac.uk