We show that if Cdk5 fails to facilitate CASK, then there is a very profound defect in synapse formation, .... The most accepted hypothesis for autism is that there is a defect in synapse formation," .... mutations of genes directly connected to CASK have already been identified as being associated with autism.
Li-Huei Tsai, PhD, and Picower Professor of Neuroscience at the Massachusetts Institute of Technology (MIT)
autism
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